Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America.
Identifieur interne : 001888 ( Main/Exploration ); précédent : 001887; suivant : 001889Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America.
Auteurs : C H Spencer [États-Unis] ; K. Rouster-Stevens [États-Unis] ; H. Gewanter [États-Unis] ; G. Syverson [États-Unis] ; R. Modica [États-Unis] ; K. Schmidt [États-Unis] ; H. Emery [États-Unis] ; C. Wallace [États-Unis] ; S. Grevich [États-Unis] ; K. Nanda [États-Unis] ; Y D Zhao [États-Unis] ; S. Shenoi [États-Unis] ; S. Tarvin [Inde] ; S. Hong [États-Unis] ; C. Lindsley [États-Unis] ; J E Weiss [États-Unis] ; M. Passo [États-Unis] ; K. Ede [États-Unis] ; A. Brown [États-Unis] ; K. Ardalan [États-Unis] ; W. Bernal [États-Unis] ; M L Stoll [États-Unis] ; B. Lang [Canada] ; R. Carrasco [États-Unis] ; C. Agaiar [États-Unis] ; L. Feller [États-Unis] ; H. Bukulmez [États-Unis] ; R. Vehe [États-Unis] ; H. Kim [États-Unis] ; H. Schmeling [Canada] ; D. Gerstbacher [États-Unis] ; M. Hoeltzel [États-Unis] ; B. Eberhard [États-Unis] ; R. Sundel [États-Unis] ; S. Kim [États-Unis] ; A M Huber [Canada] ; A. Patwardhan [États-Unis]Source :
- Pediatric rheumatology online journal [ 1546-0096 ] ; 2017.
Descripteurs français
- KwdFr :
- Antirhumatismaux (usage thérapeutique), Association de médicaments (), Association de médicaments (tendances), Biothérapie (), Dermatomyosite (), Dermatomyosite (épidémiologie), Enfant, Enquêtes et questionnaires, Femelle, Gestion de la pharmacothérapie (tendances), Glucocorticoïdes (usage thérapeutique), Humains, Infliximab (usage thérapeutique), Mâle, Méthotrexate (usage thérapeutique), Pédiatrie (), Pédiatrie (tendances), Rituximab (usage thérapeutique), Résistance à la maladie, Types de pratiques des médecins (), Étanercept (usage thérapeutique), États-Unis d'Amérique (épidémiologie).
- MESH :
- tendances : Association de médicaments, Gestion de la pharmacothérapie, Pédiatrie.
- usage thérapeutique : Antirhumatismaux, Glucocorticoïdes, Infliximab, Méthotrexate, Rituximab, Étanercept.
- épidémiologie : Dermatomyosite, États-Unis d'Amérique.
- Association de médicaments, Biothérapie, Dermatomyosite, Enfant, Enquêtes et questionnaires, Femelle, Humains, Mâle, Pédiatrie, Résistance à la maladie, Types de pratiques des médecins.
English descriptors
- KwdEn :
- Antirheumatic Agents (therapeutic use), Biological Therapy (methods), Child, Dermatomyositis (epidemiology), Dermatomyositis (therapy), Disease Resistance, Drug Therapy, Combination (classification), Drug Therapy, Combination (methods), Drug Therapy, Combination (trends), Etanercept (therapeutic use), Female, Glucocorticoids (therapeutic use), Humans, Infliximab (therapeutic use), Male, Medication Therapy Management (trends), Methotrexate (therapeutic use), Pediatrics (methods), Pediatrics (trends), Practice Patterns, Physicians' (statistics & numerical data), Rituximab (therapeutic use), Surveys and Questionnaires, United States (epidemiology).
- MESH :
- chemical , therapeutic use : Antirheumatic Agents, Etanercept, Glucocorticoids, Infliximab, Methotrexate, Rituximab.
- classification : Drug Therapy, Combination.
- epidemiology : Dermatomyositis, United States.
- methods : Biological Therapy, Drug Therapy, Combination, Pediatrics.
- statistics & numerical data : Practice Patterns, Physicians'.
- therapy : Dermatomyositis.
- trends : Drug Therapy, Combination, Medication Therapy Management, Pediatrics.
- Child, Disease Resistance, Female, Humans, Male, Surveys and Questionnaires.
Abstract
The prognosis of children with juvenile dermatomyositis (JDM) has improved remarkably since the 1960's with the use of corticosteroid and immunosuppressive therapy. Yet there remain a minority of children who have refractory disease. Since 2003 the sporadic use of biologics (genetically-engineered proteins that usually are derived from human genes) for inflammatory myositis has been reported. In 2011-2016 we investigated our collective experience of biologics in JDM through the Childhood Arthritis and Rheumatology Research Alliance (CARRA).
DOI: 10.1186/s12969-017-0174-0
PubMed: 28610606
Affiliations:
- Canada, Inde, États-Unis
- Alabama, Alberta, Arizona, Californie, Caroline du Sud, Floride, Géorgie (États-Unis), Illinois, Iowa, Kansas, Kentucky, Maine (État), Maryland, Massachusetts, Michigan, Minnesota, Missouri (État), New Jersey, Ohio, Texas, Virginie, Washington (État), Wisconsin
- Calgary, Columbia (Caroline du Sud), Seattle
- Université de Calgary, Université de Caroline du Sud, Université de Washington
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Le document en format XML
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Tarvin</name><affiliation wicri:level="1"><nlm:affiliation>Riley Hospital for Children, Indiana University Medical Center, Indianapolis, IN, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Riley Hospital for Children, Indiana University Medical Center, Indianapolis, IN</wicri:regionArea><wicri:noRegion>IN</wicri:noRegion></affiliation></author><author><name sortKey="Hong, S" sort="Hong, S" uniqKey="Hong S" first="S" last="Hong">S. Hong</name><affiliation wicri:level="2"><nlm:affiliation>University of Iowa Health Care, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Iowa Health Care, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region></placeName></affiliation></author><author><name sortKey="Lindsley, C" sort="Lindsley, C" uniqKey="Lindsley C" first="C" last="Lindsley">C. Lindsley</name><affiliation wicri:level="2"><nlm:affiliation>University of Kansas Medical Center, Kansas City, KS, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Kansas Medical Center, Kansas City, KS</wicri:regionArea><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Weiss, J E" sort="Weiss, J E" uniqKey="Weiss J" first="J E" last="Weiss">J E Weiss</name><affiliation wicri:level="2"><nlm:affiliation>Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Passo, M" sort="Passo, M" uniqKey="Passo M" first="M" last="Passo">M. Passo</name><affiliation wicri:level="4"><nlm:affiliation>University of South Carolina, Charleston, SC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of South Carolina, Charleston, SC</wicri:regionArea><placeName><region type="state">Caroline du Sud</region><settlement type="city">Columbia (Caroline du Sud)</settlement></placeName><orgName type="university">Université de Caroline du Sud</orgName></affiliation></author><author><name sortKey="Ede, K" sort="Ede, K" uniqKey="Ede K" first="K" last="Ede">K. Ede</name><affiliation wicri:level="2"><nlm:affiliation>Phoenix Children's Hospital, Phoenix, AZ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Phoenix Children's Hospital, Phoenix, AZ</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Brown, A" sort="Brown, A" uniqKey="Brown A" first="A" last="Brown">A. Brown</name><affiliation wicri:level="2"><nlm:affiliation>Texas Children's Hospital, Houston, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Texas Children's Hospital, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Ardalan, K" sort="Ardalan, K" uniqKey="Ardalan K" first="K" last="Ardalan">K. Ardalan</name><affiliation wicri:level="2"><nlm:affiliation>Lurie Children's Hospital, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lurie Children's Hospital, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Bernal, W" sort="Bernal, W" uniqKey="Bernal W" first="W" last="Bernal">W. Bernal</name><affiliation wicri:level="2"><nlm:affiliation>University of California, San Francisco, San Francisco, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Stoll, M L" sort="Stoll, M L" uniqKey="Stoll M" first="M L" last="Stoll">M L Stoll</name><affiliation wicri:level="2"><nlm:affiliation>University of Alabama at Birmingham, Birmingham, AL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Alabama at Birmingham, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Lang, B" sort="Lang, B" uniqKey="Lang B" first="B" last="Lang">B. Lang</name><affiliation wicri:level="1"><nlm:affiliation>WK Health Center and Dalhousie University, Halifax, NS, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>WK Health Center and Dalhousie University, Halifax, NS</wicri:regionArea><wicri:noRegion>NS</wicri:noRegion></affiliation></author><author><name sortKey="Carrasco, R" sort="Carrasco, R" uniqKey="Carrasco R" first="R" last="Carrasco">R. Carrasco</name><affiliation wicri:level="2"><nlm:affiliation>Dell Children's Hospital, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dell Children's Hospital, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Agaiar, C" sort="Agaiar, C" uniqKey="Agaiar C" first="C" last="Agaiar">C. Agaiar</name><affiliation wicri:level="2"><nlm:affiliation>Children's Hospital of The Kings Daughter, Norfolk, VA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Children's Hospital of The Kings Daughter, Norfolk, VA</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Feller, L" sort="Feller, L" uniqKey="Feller L" first="L" last="Feller">L. Feller</name><affiliation wicri:level="2"><nlm:affiliation>Inland Rheumatology, Waterville, ME, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Inland Rheumatology, Waterville, ME</wicri:regionArea><placeName><region type="state">Maine (État)</region></placeName></affiliation></author><author><name sortKey="Bukulmez, H" sort="Bukulmez, H" uniqKey="Bukulmez H" first="H" last="Bukulmez">H. Bukulmez</name><affiliation wicri:level="2"><nlm:affiliation>Metro Health Medical Center and Case Western Reserve University, Cleveland, OH, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Metro Health Medical Center and Case Western Reserve University, Cleveland, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Vehe, R" sort="Vehe, R" uniqKey="Vehe R" first="R" last="Vehe">R. Vehe</name><affiliation wicri:level="2"><nlm:affiliation>University of Minnesota, Minneapolis, MN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Minnesota, Minneapolis, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Kim, H" sort="Kim, H" uniqKey="Kim H" first="H" last="Kim">H. Kim</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schmeling, H" sort="Schmeling, H" uniqKey="Schmeling H" first="H" last="Schmeling">H. Schmeling</name><affiliation wicri:level="4"><nlm:affiliation>Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, AB</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Gerstbacher, D" sort="Gerstbacher, D" uniqKey="Gerstbacher D" first="D" last="Gerstbacher">D. Gerstbacher</name><affiliation wicri:level="2"><nlm:affiliation>Lucille Packard Children's Hospital, Stanford University, Stanford, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lucille Packard Children's Hospital, Stanford University, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Hoeltzel, M" sort="Hoeltzel, M" uniqKey="Hoeltzel M" first="M" last="Hoeltzel">M. Hoeltzel</name><affiliation wicri:level="2"><nlm:affiliation>Mott Children's Hospital, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Mott Children's Hospital, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Eberhard, B" sort="Eberhard, B" uniqKey="Eberhard B" first="B" last="Eberhard">B. Eberhard</name><affiliation wicri:level="1"><nlm:affiliation>Cohen Children's Medical Center of New York, New york, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cohen Children's Medical Center of New York, New york</wicri:regionArea><wicri:noRegion>New york</wicri:noRegion></affiliation></author><author><name sortKey="Sundel, R" sort="Sundel, R" uniqKey="Sundel R" first="R" last="Sundel">R. Sundel</name><affiliation wicri:level="2"><nlm:affiliation>Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston Children's Hospital and Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kim, S" sort="Kim, S" uniqKey="Kim S" first="S" last="Kim">S. Kim</name><affiliation wicri:level="2"><nlm:affiliation>University of California, San Francisco, San Francisco, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Huber, A M" sort="Huber, A M" uniqKey="Huber A" first="A M" last="Huber">A M Huber</name><affiliation wicri:level="1"><nlm:affiliation>WK Health Center and Dalhousie University, Halifax, NS, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>WK Health Center and Dalhousie University, Halifax, NS</wicri:regionArea><wicri:noRegion>NS</wicri:noRegion></affiliation></author><author><name sortKey="Patwardhan, A" sort="Patwardhan, A" uniqKey="Patwardhan A" first="A" last="Patwardhan">A. Patwardhan</name><affiliation wicri:level="2"><nlm:affiliation>School of Medicine, University of Missouri, Columbia, MO, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Medicine, University of Missouri, Columbia, MO</wicri:regionArea><placeName><region type="state">Missouri (État)</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28610606</idno><idno type="pmid">28610606</idno><idno type="doi">10.1186/s12969-017-0174-0</idno><idno type="wicri:Area/PubMed/Corpus">000B12</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B12</idno><idno type="wicri:Area/PubMed/Curation">000B12</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B12</idno><idno type="wicri:Area/PubMed/Checkpoint">000C17</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000C17</idno><idno type="wicri:Area/Ncbi/Merge">001618</idno><idno type="wicri:Area/Ncbi/Curation">001618</idno><idno type="wicri:Area/Ncbi/Checkpoint">001618</idno><idno type="wicri:Area/Main/Merge">001887</idno><idno type="wicri:Area/Main/Curation">001888</idno><idno type="wicri:Area/Main/Exploration">001888</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America.</title><author><name sortKey="Spencer, C H" sort="Spencer, C H" uniqKey="Spencer C" first="C H" last="Spencer">C H Spencer</name><affiliation wicri:level="2"><nlm:affiliation>Nationwide Children's Hospital and Ohio State University, Columbus, OH, USA. spencercharlesh1@gmail.com.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Nationwide Children's Hospital and Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Rouster Stevens, K" sort="Rouster Stevens, K" uniqKey="Rouster Stevens K" first="K" last="Rouster-Stevens">K. Rouster-Stevens</name><affiliation wicri:level="2"><nlm:affiliation>Emory University School of Medicine, Atlanta, GA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Emory University School of Medicine, Atlanta, GA</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Gewanter, H" sort="Gewanter, H" uniqKey="Gewanter H" first="H" last="Gewanter">H. Gewanter</name><affiliation wicri:level="2"><nlm:affiliation>Pediatric and Adolescent Health Partners, Richmond, VA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pediatric and Adolescent Health Partners, Richmond, VA</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Syverson, G" sort="Syverson, G" uniqKey="Syverson G" first="G" last="Syverson">G. Syverson</name><affiliation wicri:level="2"><nlm:affiliation>University of Wisconsin-Madison, Madison, WI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Wisconsin-Madison, Madison, WI</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Modica, R" sort="Modica, R" uniqKey="Modica R" first="R" last="Modica">R. Modica</name><affiliation wicri:level="2"><nlm:affiliation>University of Florida, Gainesville, FL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Florida, Gainesville, FL</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Schmidt, K" sort="Schmidt, K" uniqKey="Schmidt K" first="K" last="Schmidt">K. Schmidt</name><affiliation wicri:level="2"><nlm:affiliation>University of Louisville, Louisville, KY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Louisville, Louisville, KY</wicri:regionArea><placeName><region type="state">Kentucky</region></placeName></affiliation></author><author><name sortKey="Emery, H" sort="Emery, H" uniqKey="Emery H" first="H" last="Emery">H. Emery</name><affiliation wicri:level="4"><nlm:affiliation>Seattle Children's Hospital, University of Washington, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Children's Hospital, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Wallace, C" sort="Wallace, C" uniqKey="Wallace C" first="C" last="Wallace">C. Wallace</name><affiliation wicri:level="4"><nlm:affiliation>Seattle Children's Hospital, University of Washington, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Children's Hospital, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Grevich, S" sort="Grevich, S" uniqKey="Grevich S" first="S" last="Grevich">S. Grevich</name><affiliation wicri:level="4"><nlm:affiliation>Seattle Children's Hospital, University of Washington, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Children's Hospital, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Nanda, K" sort="Nanda, K" uniqKey="Nanda K" first="K" last="Nanda">K. Nanda</name><affiliation wicri:level="4"><nlm:affiliation>Seattle Children's Hospital, University of Washington, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Children's Hospital, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Zhao, Y D" sort="Zhao, Y D" uniqKey="Zhao Y" first="Y D" last="Zhao">Y D Zhao</name><affiliation wicri:level="4"><nlm:affiliation>Seattle Children's Hospital, University of Washington, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Children's Hospital, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Shenoi, S" sort="Shenoi, S" uniqKey="Shenoi S" first="S" last="Shenoi">S. Shenoi</name><affiliation wicri:level="4"><nlm:affiliation>Seattle Children's Hospital, University of Washington, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Children's Hospital, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Tarvin, S" sort="Tarvin, S" uniqKey="Tarvin S" first="S" last="Tarvin">S. Tarvin</name><affiliation wicri:level="1"><nlm:affiliation>Riley Hospital for Children, Indiana University Medical Center, Indianapolis, IN, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Riley Hospital for Children, Indiana University Medical Center, Indianapolis, IN</wicri:regionArea><wicri:noRegion>IN</wicri:noRegion></affiliation></author><author><name sortKey="Hong, S" sort="Hong, S" uniqKey="Hong S" first="S" last="Hong">S. Hong</name><affiliation wicri:level="2"><nlm:affiliation>University of Iowa Health Care, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Iowa Health Care, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region></placeName></affiliation></author><author><name sortKey="Lindsley, C" sort="Lindsley, C" uniqKey="Lindsley C" first="C" last="Lindsley">C. Lindsley</name><affiliation wicri:level="2"><nlm:affiliation>University of Kansas Medical Center, Kansas City, KS, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Kansas Medical Center, Kansas City, KS</wicri:regionArea><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Weiss, J E" sort="Weiss, J E" uniqKey="Weiss J" first="J E" last="Weiss">J E Weiss</name><affiliation wicri:level="2"><nlm:affiliation>Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Passo, M" sort="Passo, M" uniqKey="Passo M" first="M" last="Passo">M. Passo</name><affiliation wicri:level="4"><nlm:affiliation>University of South Carolina, Charleston, SC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of South Carolina, Charleston, SC</wicri:regionArea><placeName><region type="state">Caroline du Sud</region><settlement type="city">Columbia (Caroline du Sud)</settlement></placeName><orgName type="university">Université de Caroline du Sud</orgName></affiliation></author><author><name sortKey="Ede, K" sort="Ede, K" uniqKey="Ede K" first="K" last="Ede">K. Ede</name><affiliation wicri:level="2"><nlm:affiliation>Phoenix Children's Hospital, Phoenix, AZ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Phoenix Children's Hospital, Phoenix, AZ</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Brown, A" sort="Brown, A" uniqKey="Brown A" first="A" last="Brown">A. Brown</name><affiliation wicri:level="2"><nlm:affiliation>Texas Children's Hospital, Houston, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Texas Children's Hospital, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Ardalan, K" sort="Ardalan, K" uniqKey="Ardalan K" first="K" last="Ardalan">K. Ardalan</name><affiliation wicri:level="2"><nlm:affiliation>Lurie Children's Hospital, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lurie Children's Hospital, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Bernal, W" sort="Bernal, W" uniqKey="Bernal W" first="W" last="Bernal">W. Bernal</name><affiliation wicri:level="2"><nlm:affiliation>University of California, San Francisco, San Francisco, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Stoll, M L" sort="Stoll, M L" uniqKey="Stoll M" first="M L" last="Stoll">M L Stoll</name><affiliation wicri:level="2"><nlm:affiliation>University of Alabama at Birmingham, Birmingham, AL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Alabama at Birmingham, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Lang, B" sort="Lang, B" uniqKey="Lang B" first="B" last="Lang">B. Lang</name><affiliation wicri:level="1"><nlm:affiliation>WK Health Center and Dalhousie University, Halifax, NS, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>WK Health Center and Dalhousie University, Halifax, NS</wicri:regionArea><wicri:noRegion>NS</wicri:noRegion></affiliation></author><author><name sortKey="Carrasco, R" sort="Carrasco, R" uniqKey="Carrasco R" first="R" last="Carrasco">R. Carrasco</name><affiliation wicri:level="2"><nlm:affiliation>Dell Children's Hospital, Austin, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dell Children's Hospital, Austin, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Agaiar, C" sort="Agaiar, C" uniqKey="Agaiar C" first="C" last="Agaiar">C. Agaiar</name><affiliation wicri:level="2"><nlm:affiliation>Children's Hospital of The Kings Daughter, Norfolk, VA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Children's Hospital of The Kings Daughter, Norfolk, VA</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Feller, L" sort="Feller, L" uniqKey="Feller L" first="L" last="Feller">L. Feller</name><affiliation wicri:level="2"><nlm:affiliation>Inland Rheumatology, Waterville, ME, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Inland Rheumatology, Waterville, ME</wicri:regionArea><placeName><region type="state">Maine (État)</region></placeName></affiliation></author><author><name sortKey="Bukulmez, H" sort="Bukulmez, H" uniqKey="Bukulmez H" first="H" last="Bukulmez">H. Bukulmez</name><affiliation wicri:level="2"><nlm:affiliation>Metro Health Medical Center and Case Western Reserve University, Cleveland, OH, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Metro Health Medical Center and Case Western Reserve University, Cleveland, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Vehe, R" sort="Vehe, R" uniqKey="Vehe R" first="R" last="Vehe">R. Vehe</name><affiliation wicri:level="2"><nlm:affiliation>University of Minnesota, Minneapolis, MN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Minnesota, Minneapolis, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Kim, H" sort="Kim, H" uniqKey="Kim H" first="H" last="Kim">H. Kim</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schmeling, H" sort="Schmeling, H" uniqKey="Schmeling H" first="H" last="Schmeling">H. Schmeling</name><affiliation wicri:level="4"><nlm:affiliation>Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, AB</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Gerstbacher, D" sort="Gerstbacher, D" uniqKey="Gerstbacher D" first="D" last="Gerstbacher">D. Gerstbacher</name><affiliation wicri:level="2"><nlm:affiliation>Lucille Packard Children's Hospital, Stanford University, Stanford, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lucille Packard Children's Hospital, Stanford University, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Hoeltzel, M" sort="Hoeltzel, M" uniqKey="Hoeltzel M" first="M" last="Hoeltzel">M. Hoeltzel</name><affiliation wicri:level="2"><nlm:affiliation>Mott Children's Hospital, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Mott Children's Hospital, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Eberhard, B" sort="Eberhard, B" uniqKey="Eberhard B" first="B" last="Eberhard">B. Eberhard</name><affiliation wicri:level="1"><nlm:affiliation>Cohen Children's Medical Center of New York, New york, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cohen Children's Medical Center of New York, New york</wicri:regionArea><wicri:noRegion>New york</wicri:noRegion></affiliation></author><author><name sortKey="Sundel, R" sort="Sundel, R" uniqKey="Sundel R" first="R" last="Sundel">R. Sundel</name><affiliation wicri:level="2"><nlm:affiliation>Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston Children's Hospital and Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kim, S" sort="Kim, S" uniqKey="Kim S" first="S" last="Kim">S. Kim</name><affiliation wicri:level="2"><nlm:affiliation>University of California, San Francisco, San Francisco, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Huber, A M" sort="Huber, A M" uniqKey="Huber A" first="A M" last="Huber">A M Huber</name><affiliation wicri:level="1"><nlm:affiliation>WK Health Center and Dalhousie University, Halifax, NS, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>WK Health Center and Dalhousie University, Halifax, NS</wicri:regionArea><wicri:noRegion>NS</wicri:noRegion></affiliation></author><author><name sortKey="Patwardhan, A" sort="Patwardhan, A" uniqKey="Patwardhan A" first="A" last="Patwardhan">A. Patwardhan</name><affiliation wicri:level="2"><nlm:affiliation>School of Medicine, University of Missouri, Columbia, MO, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Medicine, University of Missouri, Columbia, MO</wicri:regionArea><placeName><region type="state">Missouri (État)</region></placeName></affiliation></author></analytic><series><title level="j">Pediatric rheumatology online journal</title><idno type="eISSN">1546-0096</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antirheumatic Agents (therapeutic use)</term><term>Biological Therapy (methods)</term><term>Child</term><term>Dermatomyositis (epidemiology)</term><term>Dermatomyositis (therapy)</term><term>Disease Resistance</term><term>Drug Therapy, Combination (classification)</term><term>Drug Therapy, Combination (methods)</term><term>Drug Therapy, Combination (trends)</term><term>Etanercept (therapeutic use)</term><term>Female</term><term>Glucocorticoids (therapeutic use)</term><term>Humans</term><term>Infliximab (therapeutic use)</term><term>Male</term><term>Medication Therapy Management (trends)</term><term>Methotrexate (therapeutic use)</term><term>Pediatrics (methods)</term><term>Pediatrics (trends)</term><term>Practice Patterns, Physicians' (statistics & numerical data)</term><term>Rituximab (therapeutic use)</term><term>Surveys and Questionnaires</term><term>United States (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antirhumatismaux (usage thérapeutique)</term><term>Association de médicaments ()</term><term>Association de médicaments (tendances)</term><term>Biothérapie ()</term><term>Dermatomyosite ()</term><term>Dermatomyosite (épidémiologie)</term><term>Enfant</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Gestion de la pharmacothérapie (tendances)</term><term>Glucocorticoïdes (usage thérapeutique)</term><term>Humains</term><term>Infliximab (usage thérapeutique)</term><term>Mâle</term><term>Méthotrexate (usage thérapeutique)</term><term>Pédiatrie ()</term><term>Pédiatrie (tendances)</term><term>Rituximab (usage thérapeutique)</term><term>Résistance à la maladie</term><term>Types de pratiques des médecins ()</term><term>Étanercept (usage thérapeutique)</term><term>États-Unis d'Amérique (épidémiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antirheumatic Agents</term><term>Etanercept</term><term>Glucocorticoids</term><term>Infliximab</term><term>Methotrexate</term><term>Rituximab</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Drug Therapy, Combination</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Dermatomyositis</term><term>United States</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Biological Therapy</term><term>Drug Therapy, Combination</term><term>Pediatrics</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Practice Patterns, Physicians'</term></keywords><keywords scheme="MESH" qualifier="tendances" xml:lang="fr"><term>Association de médicaments</term><term>Gestion de la pharmacothérapie</term><term>Pédiatrie</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dermatomyositis</term></keywords><keywords scheme="MESH" qualifier="trends" xml:lang="en"><term>Drug Therapy, Combination</term><term>Medication Therapy Management</term><term>Pediatrics</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antirhumatismaux</term><term>Glucocorticoïdes</term><term>Infliximab</term><term>Méthotrexate</term><term>Rituximab</term><term>Étanercept</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Dermatomyosite</term><term>États-Unis d'Amérique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child</term><term>Disease Resistance</term><term>Female</term><term>Humans</term><term>Male</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Association de médicaments</term><term>Biothérapie</term><term>Dermatomyosite</term><term>Enfant</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Pédiatrie</term><term>Résistance à la maladie</term><term>Types de pratiques des médecins</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The prognosis of children with juvenile dermatomyositis (JDM) has improved remarkably since the 1960's with the use of corticosteroid and immunosuppressive therapy. Yet there remain a minority of children who have refractory disease. Since 2003 the sporadic use of biologics (genetically-engineered proteins that usually are derived from human genes) for inflammatory myositis has been reported. In 2011-2016 we investigated our collective experience of biologics in JDM through the Childhood Arthritis and Rheumatology Research Alliance (CARRA).</div></front></TEI><affiliations><list><country><li>Canada</li><li>Inde</li><li>États-Unis</li></country><region><li>Alabama</li><li>Alberta</li><li>Arizona</li><li>Californie</li><li>Caroline du Sud</li><li>Floride</li><li>Géorgie (États-Unis)</li><li>Illinois</li><li>Iowa</li><li>Kansas</li><li>Kentucky</li><li>Maine (État)</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Minnesota</li><li>Missouri (État)</li><li>New Jersey</li><li>Ohio</li><li>Texas</li><li>Virginie</li><li>Washington (État)</li><li>Wisconsin</li></region><settlement><li>Calgary</li><li>Columbia (Caroline du Sud)</li><li>Seattle</li></settlement><orgName><li>Université de Calgary</li><li>Université de Caroline du Sud</li><li>Université de Washington</li></orgName></list><tree><country name="États-Unis"><region name="Ohio"><name sortKey="Spencer, C H" sort="Spencer, C H" uniqKey="Spencer C" first="C H" last="Spencer">C H Spencer</name></region><name sortKey="Agaiar, C" sort="Agaiar, C" uniqKey="Agaiar C" first="C" last="Agaiar">C. Agaiar</name><name sortKey="Ardalan, K" sort="Ardalan, K" uniqKey="Ardalan K" first="K" last="Ardalan">K. Ardalan</name><name sortKey="Bernal, W" sort="Bernal, W" uniqKey="Bernal W" first="W" last="Bernal">W. Bernal</name><name sortKey="Brown, A" sort="Brown, A" uniqKey="Brown A" first="A" last="Brown">A. Brown</name><name sortKey="Bukulmez, H" sort="Bukulmez, H" uniqKey="Bukulmez H" first="H" last="Bukulmez">H. Bukulmez</name><name sortKey="Carrasco, R" sort="Carrasco, R" uniqKey="Carrasco R" first="R" last="Carrasco">R. Carrasco</name><name sortKey="Eberhard, B" sort="Eberhard, B" uniqKey="Eberhard B" first="B" last="Eberhard">B. Eberhard</name><name sortKey="Ede, K" sort="Ede, K" uniqKey="Ede K" first="K" last="Ede">K. Ede</name><name sortKey="Emery, H" sort="Emery, H" uniqKey="Emery H" first="H" last="Emery">H. Emery</name><name sortKey="Feller, L" sort="Feller, L" uniqKey="Feller L" first="L" last="Feller">L. Feller</name><name sortKey="Gerstbacher, D" sort="Gerstbacher, D" uniqKey="Gerstbacher D" first="D" last="Gerstbacher">D. Gerstbacher</name><name sortKey="Gewanter, H" sort="Gewanter, H" uniqKey="Gewanter H" first="H" last="Gewanter">H. Gewanter</name><name sortKey="Grevich, S" sort="Grevich, S" uniqKey="Grevich S" first="S" last="Grevich">S. Grevich</name><name sortKey="Hoeltzel, M" sort="Hoeltzel, M" uniqKey="Hoeltzel M" first="M" last="Hoeltzel">M. Hoeltzel</name><name sortKey="Hong, S" sort="Hong, S" uniqKey="Hong S" first="S" last="Hong">S. Hong</name><name sortKey="Kim, H" sort="Kim, H" uniqKey="Kim H" first="H" last="Kim">H. Kim</name><name sortKey="Kim, S" sort="Kim, S" uniqKey="Kim S" first="S" last="Kim">S. Kim</name><name sortKey="Lindsley, C" sort="Lindsley, C" uniqKey="Lindsley C" first="C" last="Lindsley">C. Lindsley</name><name sortKey="Modica, R" sort="Modica, R" uniqKey="Modica R" first="R" last="Modica">R. Modica</name><name sortKey="Nanda, K" sort="Nanda, K" uniqKey="Nanda K" first="K" last="Nanda">K. Nanda</name><name sortKey="Passo, M" sort="Passo, M" uniqKey="Passo M" first="M" last="Passo">M. Passo</name><name sortKey="Patwardhan, A" sort="Patwardhan, A" uniqKey="Patwardhan A" first="A" last="Patwardhan">A. Patwardhan</name><name sortKey="Rouster Stevens, K" sort="Rouster Stevens, K" uniqKey="Rouster Stevens K" first="K" last="Rouster-Stevens">K. Rouster-Stevens</name><name sortKey="Schmidt, K" sort="Schmidt, K" uniqKey="Schmidt K" first="K" last="Schmidt">K. Schmidt</name><name sortKey="Shenoi, S" sort="Shenoi, S" uniqKey="Shenoi S" first="S" last="Shenoi">S. Shenoi</name><name sortKey="Stoll, M L" sort="Stoll, M L" uniqKey="Stoll M" first="M L" last="Stoll">M L Stoll</name><name sortKey="Sundel, R" sort="Sundel, R" uniqKey="Sundel R" first="R" last="Sundel">R. Sundel</name><name sortKey="Syverson, G" sort="Syverson, G" uniqKey="Syverson G" first="G" last="Syverson">G. Syverson</name><name sortKey="Vehe, R" sort="Vehe, R" uniqKey="Vehe R" first="R" last="Vehe">R. Vehe</name><name sortKey="Wallace, C" sort="Wallace, C" uniqKey="Wallace C" first="C" last="Wallace">C. Wallace</name><name sortKey="Weiss, J E" sort="Weiss, J E" uniqKey="Weiss J" first="J E" last="Weiss">J E Weiss</name><name sortKey="Zhao, Y D" sort="Zhao, Y D" uniqKey="Zhao Y" first="Y D" last="Zhao">Y D Zhao</name></country><country name="Inde"><noRegion><name sortKey="Tarvin, S" sort="Tarvin, S" uniqKey="Tarvin S" first="S" last="Tarvin">S. Tarvin</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Lang, B" sort="Lang, B" uniqKey="Lang B" first="B" last="Lang">B. Lang</name></noRegion><name sortKey="Huber, A M" sort="Huber, A M" uniqKey="Huber A" first="A M" last="Huber">A M Huber</name><name sortKey="Schmeling, H" sort="Schmeling, H" uniqKey="Schmeling H" first="H" last="Schmeling">H. Schmeling</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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